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Inherited cerebellar ataxia in childhood a pattern-recognition approach using brain MRI

LEONARDO MODESTI VEDOLIN, G. GONZALEZ, C. LOURENÇO, CF SOUZA, AJ BARKOVICH

American Journal of Neuroradiology, v. 34, n. 5, p. 925-934, 2013.

Motivo: Produção Colaborador HMV

Setor HMV: UDI - Gerência, Neurorradiologia

Área da saúde: Radiologia e Diagnóstico por Imagem

Resumo: Ataxia is the principal symptom of many common neurologic diseases in childhood. Ataxias caused by dysfunction of the cerebellum occur in acute, intermittent, and progressive disorders. Most of the chronic progressive processes are secondary to degenerative and metabolic diseases. In addition, congenital malformation of the midbrain and hindbrain can also be present, with posterior fossa symptoms related to ataxia. Brain MR imaging is the most accurate imaging technique to investigate these patients, and imaging abnormalities include size, shape, and/or signal of the brain stem and/or cerebellum. Supratentorial and cord lesions are also common. This review will discuss a pattern-recognition approach to inherited cerebellar ataxia in childhood. The purpose is to provide a comprehensive discussion that ultimately could help neuroradiologists better manage this important topic in pediatric neurology.

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